Sigma-Aldrich Corp.    



3050 Spruce St.

Saint Louis, MO 63103-2530

United States

(314) 771-5765

(314) 771-5757

Company description

Sigma-Aldrich Corp. was incorporated in Delaware in 1975, as the successor to Sigma Chemical Company and Aldrich Chemical Company Inc., both of which had operated continuously for more than 20 years. The life science and high technology company develops, manufactures, purchases and distributes chemicals, biochemicals and equipment worldwide. These chemical products and kits are used in scientific research, including genomic and proteomic research, biotechnology, pharmaceutical development and as key components in pharmaceutical, diagnostic and other high technology manufacturing. Sigma-Aldrich is organized into four research units: essentials, specialties, biotech and fine chemicals (SAFC). The essentials unit sells biological buffers, cell culture reagents, biochemicals, chemicals, solvents, and other reagents and kits. These products are typically sold in higher volumes to economic research buyers. The specialties unit sells organic chemicals, biochemicals, analytical reagents, chromatography and other laboratory consumables, reference materials and high-purity products; which are generally sold in smaller volumes to the lab scientist customer. The biotech unit supplies immunochemical, molecular biology, cell biology, proteomic, genomic, transgenic and other life science products to academic, government, industrial, biotechnology and pharmaceutical research customers. The SAFC unit supplies large-scale organic chemicals and biochemicals used in development and production by pharmaceutical, biotechnology, industrial, diagnostic and electronics companies. Headquartered in St. Louis, Mo., the company operates in 38 countries, manufacturing approximately 48,000 of the 130,000 chemical products it offers. Sigma-Aldrich also offers approximately 40,000 equipment products. These products are sold in more than 160 countries.

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News and information about Sigma-Aldrich Corp.

United Kingdom : Johnson Matthey Appointment of Sector Chief Executive, Health
Mena Report; March 3, 2018; 376 words
...Merck KGaA, and was based in the US. Prior to that Jason was Vice President and Managing Director, Asia Pacific for the Sigma-Aldrich Corporation, based in Singapore. Jason was educated in Canada and received his MBA from Duke University USA. Robert MacLeod...
Establishment and Proteomic Characterization of a Novel Cell Line, NCC-UPS2-C1, Derived from a Patient with Undifferentiated Pleomorphic Sarcoma
In Vitro Cellular & Developmental Biology; March 1, 2018; 700+ words
...and written informed consent was obtained from the patient.Cell line establishment Tumortissue was immersed in DMEM (Sigma-Aldrich, St. Louis, MO) supplemented with 10% fetal bovine serum (FBS) (Gibco, Grand Island, NY), 100 U penicillin G...
Optimized Mass Spectrometry-Based Metabolite Extraction and Analysis for the Geographical Discrimination of White Rice (Oryza Sativa L.): A Method Comparison Study
Journal of AOAC International; March 1, 2018; 700+ words
...trifluoroacetamide (BSTFA) containing 1% trimethylchlorosilane (TMCS), methoxyamine hydrochloride, and pyridine were purchased from Sigma-Aldrich (St. Louis, MO). All reagents were analytical grade. HPLC grade solvents, which included acetonitrile, chloroform...
A Versatile Liquid Chromatographic Method for the Simultaneous Determination of Metformin, Sitagliptin, Simvastatin, and Ezetimibe in Different Dosage Forms
Journal of AOAC International; March 1, 2018; 700+ words
...Pharmaceutical Chemicals Co. (Egypt). Sodium hydroxide (Loba Chemie, Mumbai, India) and o-phosphoric acid 85% (Sigma-Aldrich, Buchs, Switzerland) were used for the pH adjustment of the buffer. All chemicals used were of analytical reagent grade...
Development and Validation of an HPLC--UV Method to Quantify Tavaborole during in Vitro Transungual Permeation Studies
Journal of AOAC International; March 1, 2018; 700+ words
...sub.3]), sodium hydroxide (NaOH), LC grade acetonitrile (ACN), and absolute ethanol (EtOH) were purchased from Sigma-Aldrich (Milan, Italy). Deionized water was purified using a Milli-RX20 system (Millipore, Molsheim, France). Preparation...
Simultaneous Spectrophotometric Determination of Elbasvir and Grazoprevir in a Pharmaceutical Preparation
Journal of AOAC International; March 1, 2018; 700+ words
...National Organization for Drug Control and Research (Giza, Egypt). Chemicals and Reagents Methanol.--HPLC grade (Sigma-Aldrich, Munich, Germany). Apparatus Shimadzu UV-Visible 1650 spectrophotometer.--Equipped with 10 mm matched quartz cells...
Validated Analytical Methods for the Determination of Drugs Used in the Treatment of Hyperemesis Gravidarum in Multiple Formulations
Journal of AOAC International; March 1, 2018; 700+ words
...each tablet claimed to contain 30 mg PYR and 50 mg CYC. Solvents and Reagents Methanol was of HPLC grade (CHROMASOLVE, Sigma-Aldrich Chemie GmbH, Germany). HCl and phosphoric acid were of analytical grade (El-Nasr Pharmaceutical Chemicals Co., Abu...
Sensitive Detection of Neonicotinoid Insecticides and Other Selected Pesticides in Pollen and Nectar Using Nanoflow Liquid Chromatography Orbitrap Tandem Mass Spectrometry
Journal of AOAC International; March 1, 2018; 700+ words
...nitenpyram, thymol, and benzyl benzoate were purchased from Sigma-Aldrich (St. Louis, MO). Individual stock solutions of the targeted...sulfate (Mg[SO.sub.4]) and sodium chloride were from Sigma-Aldrich. Sample Treatment For nectar, 20 mg samples were diluted...

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Industry information

NAICS codes 
North American Industry Classification System (NAICS) codes are used to classify businesses for the purpose of collecting statistical data related to the U.S. economy. NAICS codes have been assigned to international companies to help organize all companies by type of activity.  

Primary: 424690 - Other Chemical and Allied Products Merchant Wholesalers


SIC codes 
Standard Industrial Classification (SIC) codes classify establishments by their primary type of activity. SIC codes are a U.S. Census Bureau system but can apply to international companies.  

Primary: 5169 - Chemicals and Allied Products, NEC industry report