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Functional Assignment to JEV Proteins Using SVM
January 1, 2008 ... Background: Japanese encephalitis virus (JEV) is a mosquito borne neurotropic flavivirus, endemic-epidemic throughout Asia [1]. Severe JEV infection is marked by quick onset, headache, high fever, neck stiffness, occasional convulsions...

Role of Nitric Oxide Synthase in Insect Cell Radioresistance: An In-Silico Analysis
January 1, 2008 ... Background: Nitric oxide (NO) is a biological effector molecule that acts as a multifunctional messenger in mammalian physiology such as vasodilatation, neurotransmission, cell-cell interaction, regulation of vascular tone and...

Virtual High Throughput Screening (vHTS)-A Perspective
January 1, 2008 ... Background: The discovery of novel drug targets has increased exponentially in recent years due to advances in genomic and molecular biology techniques. Experimental and computational methods are effectively applied to accelerate the process...

Homology Modeling of Mycoplasma Pneumoniae Enolase and Its Molecular Interaction with Human Plasminogen
January 1, 2008 ... Background: Mycoplasma pneumoniae is one of the most commonly encountered pathogenic bacteria causing particular human diseases. Serious infections requiring hospitalization occur in both young adults and children. This pathogen infects not...

Phylogenetic Analysis of Chloroplast matK Gene from Zingiberaceae for Plant DNA Barcoding
January 1, 2008 ... Background: In DNA barcoding, a short DNA sequence is used as a molecular marker for identifying the diversity that exists among plant and animal species. An internal transcribed spacer (ITS) region of nuclear ribosomal cistron is the most...